A clinical study has been carried out in thirty patients with hyperprolactiemia at Chonbuk National University, Medical School in order to investigate clinical characteristics and response to medical treatment from March, 1989 to February, 1992.
@ES The results were as follows:
@EN 1. The most common cause of hyperprolacinemia was idiopathic(n=22;73.4%, and then suspected microadenoma of the pituitary gland (n=6;20%) in this study.
2. Galactorrhea was the most comon symptom(63.3%), and followed by amenorrhea or oligomenorrhea (50%), infertility (43.3%), and headache(133.3%) in order.
3. In took 5.5±1.3 weeks, 6.3±1.2 weeks, 7.2±1.3 weeks, and 9.1±1.5 weeks for normalization of serum prolactin level, resumption of regular menstruation, cessation of galactorrhea, and conception, respectively after Bromocriptine treatment.
4. The obstetrical outcome of 9 pregnancies after Bromocriptine treatment were term deliveries in 3 cases(33.3%), ongoing pregnancies in 3 cases (33.3%), spontaneous abortions in 2 cases(22.2%), and preterm delivery in 1 case(11.2%).
5. Mild dizzainess, nausea and vomiting and lethargy were observed in some patients (n=8) after Bromocriptine treatment, but any specific serious side effects were not observed in most patients(n=15).
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